Symbol
Name
ID

Zbtb7b
zinc finger and BTB domain containing 7B
MGI:102755

Phenotype annotations related to immune system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes

immune system phenotype

abnormal T cell differentiation

abnormal CD4-positive T cell differentiation

increased double-negative T cell number

abnormal double-positive T cell morphology

decreased CD4-positive, alpha-beta T cell number

absent CD4-positive, alpha-beta T cells

increased CD4-positive, alpha-beta T cell number

abnormal CD8-positive, alpha-beta T cell number

decreased CD8-positive, alpha-beta T cell number

absent CD8-positive, alpha-beta T cells

increased CD8-positive, alpha-beta T cell number

abnormal CD4-positive, alpha beta T cell morphology

abnormal CD4-positive, alpha-beta T cell physiology

abnormal humoral immune response

increased interferon-gamma secretion

Availability

Mouse Genotype

Zbtb7b^hd/Zbtb7b^hd

Zbtb7b^hpls/Zbtb7b^hpls

Zbtb7b^tm1.1Rbo/Zbtb7b^tm1.1Rbo

Zbtb7b^tm1.1Skok/Zbtb7b^tm1.1Skok

Zbtb7b^tm1Tani/Zbtb7b^tm1Tani

Zbtb7b^tm2Litt/Zbtb7b^tm2Litt

Zbtb7b^tm4.1Itan/Zbtb7b^tm4.1Itan

Zbtb7b^tm7Itan/Zbtb7b^tm7Itan

Zbtb7b^tm1Itan/Zbtb7b^tm1Tani

Zbtb7b^tm1Itan/Zbtb7b^tm2Itan

Zbtb7b^tm1Litt/Zbtb7b^tm1.2Litt

Zbtb7b^tm2Litt/Zbtb7b^tm1.2Litt

Zbtb7b^tm2Tani/Zbtb7b⁺

Tg(CD2-Zbtb7b)C8Rbo/?

Zbtb7b^tm6.1Itan/Zbtb7b^tm6.1Itan
Tg(Cd4-cre)1Cwi/? (conditional)

Zbtb7b^tm6.1Itan/Zbtb7b^tm6.1Itan
Tg(Cd8a-cre)1Itan/? (conditional)

Zbtb7b^tm2Litt/Zbtb7b^tm1.2Litt
Tg(Lck-cre)1Cwi/? (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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